Howard Coale is a former Managing Director of User Experience at Scient, and has overseen user experience strategy, complex interface design, user research, prototyping, information architecture and implementation on major Web and software projects for The Museum of Modern Art, DuPont, Johnson & Johnson, Dun & Bradstreet, MetLife, A&E, AT&T, and many others.

Before Scient, Howard was Executive Creative Director at Luminant Worldwide, and Lead Creative Director at Interactive 8, where he won awards for Web projects for The History Channel, IBM, Maybelline and M&M/Mars.

Just before founding TACITUS, Howard was Senior VP of Design & Technology at MBC in Philadelphia, focusing on building complex software and Web applications for pharma and biotech companies such as McNeil, AstraZeneca, Pfizer, Biogen and others.

Howard holds a B.A. in English Literature from Cornell and an M.F.A. in Illustration from The School of Visual Arts in New York. His drawings have appeared in The New Yorker, The Wall Street Journal, The Philadelphia Inquirer, and several books. His criticism and non-fiction have appeared in The New York Times Book Review and The New Yorker. He is a published novelist whose first novel, The Ouroboros, was well reviewed in major newspapers around the country. The Sand Men, his second novel, was recently completed.

Howard is also semi-obsessed with computer games.

Before Tacitus, Brian was Chief Technology Officer of Cognia Corporation, where he designed a $10 million Natural Language Processing TXM project and specialized in content databases and delivery.

Dr. Osborne has extensive experience in bioinformatics and software development, which he gained as the Director of Information Technology at OSI Pharmaceuticals and a Group Leader of Bioinformatics at Cadus Pharmaceuticals. He is a core contributor to the open source Bioperl bioinformatics toolkit, both in development and documentation.

Brian holds a Ph.D. in biology from MIT and did postdoctoral with the lab of Dr. Barbara Baker at U.C. Berkeley. He plays the banjo.

While working with TACITUS, Dr. Audeh is the current Chair of the Cedars-Sinai Cancer Committee and past Clinical Chief of Hematology/Oncology at Cedars-Sinai. Bill's expertise is in the treatment of many types of cancers, with emphasis on managing breast, colorectal, ovarian, and prostate cancers; he has particular interest in the area of cancer prevention, including risk assessment and genetic testing.

Bill is a noted speaker on the topic of cancer prevention and genetics and is currently Chair of the Cedars-Sinai Cancer Committee and past Clinical Chief of the Division of Hematology/Oncology.  He is also Assistant Professor of Medicine at the University of California, Los Angeles (UCLA) School of Medicine.

Bill directs TACITUS's strategy for product and software development focused on clinical and biotech applications.

In addition to his work leading computational biology at TACITUS, Rich is a pioneer in the new field of Systems Biology, and is a faculty member at New York University's Center for Comparative Functional Genomics, where he is a joint member of both the Biology and Computer Science departments. His laboratory at NYU is focused on making computational tools, algorithms and methods for systems-wide elucidation of biological systems. His research aims to develop computational methods at the intersection of two interrelated fields: protein structure and functional genomics. Rich is also currently the technical lead on two grid computing collaborations with IBM -- the first and second phases of the Human Proteome Folding Project.

Rich did his doctoral work at the University of Washington in Seattle working with David Baker on the state of the art protein structure modeling and prediction, and played a critical role in the development and deployment of the protein unfolding program "Rosetta". In Seattle, he also had the opportunity to work as a Senior Scientist -- with Nitin Baliga and Leroy Hood -- at the Institute for Systems Biology.

Rich works with TACITUS on a number of different collaborations; and advises the company on the approach to applications focused on genomics, computational biology and cell biology. He has provided the vision and creative passion, from a cientific perspective, that is critical to our unique merging of art and science.

For more on Rich's work, check out his website at:
http://homepages.nyu.edu/~rb133

Tom is an award-winning Sound Designer who has worked almost exclusively at Skywalker Sound, (George Lucas’s Post Production Facility in Northern California) for close to 20 years. Tom has plied his trade on a wide variety of projects, including feature films, animation, television, advertising, as well as video and computer games. His daily routine revolves around designing, creating and editing sound effects, integrating his work with other departments (music, dialog and foley), and mixing all of these together to create an organic whole focused on the experience of sound.
 
Tom has a particular affinity for animation. A few of his more recent notable projects include Pixar’s Cars, Star Wars Episode 3: Revenge of the Sith, Brave Story (for Fuji-TV) and Clerks 2. Tom is currently working on a series of theme park rides at Epcot Center and Disneyland for Walt Disney Imagineering.
 
Tom received his B.S. in Communications from Northwestern, then did graduate work in Film at the California State University at San Francisco. Tom, his wife and son, currently reside in Novato, California.

David earned his Doctorate in Biochemistry from Oxford University under the tutelage of Iain Campbell, in the area of protein nuclear magnetic resonance and structural biology. Furthermore, he did his postdoctoral work at the University of California, Los Angeles, where he developed methods to model protein-DNA complexes, and conducted an extensive genomic study of sortases, enzymes that anchor surface proteins to the cell walls of Gram-positive bacteria. He was also a fellow at Research Corporation Technologies, a technology investment and management company that provides early-stage funding and development for promising biomedical companies and technologies. Prior to his graduate work, David conducted research and development into plasma processing for semiconductor fabrication applications, as well as earning a degree in Mechanical Engineering from the University of Maryland.

Most recently, David was with Cognia Corporation, a firm which provides information management tools for drug discovery to pharmaceutical and biotech companies. He was also a senior bioinformatics scientist at Paracel, a subsidiary of Celera, which provided bioinformatics software and hardware platforms to the life sciences community.

David has been a long-time activist and leader in the areas of environmentalism, human rights and third world development. He has written several peer-reviewed scientific papers, as well as a proposal for the John D. and Catherine T. MacArthur Foundation Program on Global Security and Sustainability entitled, "Nature and the City: The political ecology of the environment, urbanization and sustainability."

David is a critical contributor and advisor to TACITUS on molecular biology, bioinformatics and biotechnology marketing.

Tom is a seasoned scientist and engineer with accomplishments in several fields, but whose common theme has been the creative application of science and computer technology to real-world needs.
 
Tom earned a Ph.D. in Biochemistry at Princeton in 1969, and started postdoctoral work on mitochondrial energy transduction, but soon succumbed to the lure of technology and joined a computer service company involved in financial printing (this company had one of the first IBM 360s in New York).
 
In 1972 Tom was hired by Memorial Sloan-Kettering Cancer Center as a research engineer and cell biologist.  During the next 10 years was one of the principal developers of computerized flow cytometry, now a core biomedical technology.
 
During the 1980s, he was a principal software and systems engineer for one of the pioneer magnetic resonance imaging companies, Fonar Corporation.  Later he played the same role at Otsuka Electronics (USA) and Magna-Lab, Inc., and briefly developed embedded software for Kodak’s Medical Ultrasound division (see details in CV).
 
Most recently Tom was a senior engineer with Q Systems, Inc., an electronic design consultancy, where he developed the embedded operating system for an advanced biomedical instrument, and analytical software and simulations to support the design of very-large-scale integrated circuits
 
In retirement (and a critical advisor for TACITUS), Tom has indulged his interest in genomics and bioinformatics by developing software for statistical analysis of evolutionary patterns in DNA sequences.  He has also built several panoramic cameras out of flatbed document scanners and written software to operate them.  Some of the resulting images can be seen at http://www.tksharpless.com.

Barry graduated from M.I.T. with a B.S. in Aeronautical and Astronautical Engineering, and went on to work at Cambridge Technology Partners, where he worked on diverse projects, including the design of aircraft cockpits.

After Cambridge Technology Partners, Barry became a Managing Director of User Experience at Scient (where he met Howard), and oversaw complex Web, wireless and software applications for Verizon, Citibank, Wells Fargo, Johnson & Johnson, Bertelsmann Music Group and many others.

Barry has over 15 years of experience in human factors, user research and information architecture. He advises TACITUS on large-scale Data Gaming projects, and helps to structure our approach, our implementation planning, and everything that involves hard headed, ruthless skepticism.

Barry is an avid rock climber, and has climbed death-defying rock formations in New Hampshire, Wyoming (Devil's Tower), South Dakota, Texas and Mexico.